Rheumatoid Arthritis Causes
The symptoms of rheumatoid arthritis are clearly depicted in one who suffers the illness but rheumatoid arthritis causes are still not known. The inflammation and pain that are experienced by patients suffering from rheumatoid arthritis is activated by the genetic, environmental and biological factors; abnormal functioning of the immune system and other causes such as hormonal changes or viral infection as a result of other illnesses.
Immune system’s role in rheumatoid arthritis causes
The inflammation of affected joints is the consequence of the abnormal functioning of the immune system which is responsible in healing wounds sustained by the body and recovering from body injuries and helping fight infection. The abnormal response of the immune system which is the failure to control inflammation of the injured part is one of the rheumatoid arthritis causes. Normally, when there is infection caused by illness or injury, the white blood cells are activated to relieve the system of the viruses by clotting the blood within the infected part or the injured portion to possibly heal the wound.
The inflammation caused in the area surrounding the wound as a result of an injury is normally repaired and relieved by a healthy immune system. The healthy immune system repairs the wound by clotting off bleeding blood vessel and repairing the damaged tissues. The lymphocytes called B cells and T cells are the known infection fighters of the immune system that are responsible in fighting inflammation. The chemicals produced by the T cells called cytokines help the B cells produce antibodies or immune proteins that fight infection-causing foreign bodies. These cells are overactive in rheumatoid arthritis patients as a result of a weak immune system which is attributed as one of rheumatoid arthritis causes.
Identifying rheumatoid arthritis causes
Rheumatoid arthritis causes include genetic and environmental and other factors that are not directly identified as major causes but rather contributory to its development. Genetic marker associated with rheumatoid arthritis is the human leukocyte antigen or commonly called HLA that plays important role in rheumatoid arthritis by increasing the patient’s susceptibility in developing the ailment or worsening its symptoms. The HLA are located outside the white blood cells and helps one’s immune system to function normally. Since one of the identified causes of rheumatoid arthritis is genetic factor, it is believed that a person whose father or mother is inflicted with the ailment has got higher percentage of having the same illness.
Infections caused by viruses and bacteria have been fully researched on but not a single virus or bacteria was proven to trigger the ailment and be considered as one of rheumatoid arthritis causes. Synovial fluid of rheumatoid arthritis people are noted with E. coli intestinal bacteria but are likewise ruled out as the main cause of the disease. However, the bacteria are known to affect the immune system and aid in prolonging the effects of the illness. Other common bacteria that are associated with triggering the signs of rheumatoid arthritis are retroviruses, parvovirus B19, mycoplasma, Epstein-Barr virus and mycobacteria.
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